Thrombophilia (Hypercoagulable state) (Coagulopathy)
Would you like to know what lab results mean? DDxHub - Differential Diagnosis Hub helps to understand and explains your blood test.
Thrombophilia (Hypercoagulable state) (Coagulopathy) |
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Would you like to know what lab results mean? DDxHub - Differential Diagnosis Hub helps to understand and explains your blood test. |
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You have symptoms and blood work results. How do they correlate? What is the health condition? Some disorders have similar signs and laboratory values. DDxHub helps to define a right diagnosis. Run DDxHub now and enter symptoms and test results. |
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All information on this page is intended for your general knowledge only and does not provide medical advice, diagnosis or treatment. See Additional Information |
Prothrombin thrombophilia is an inherited disorder of blood clotting. Thrombophilia is an increased tendency to form abnormal blood clots in blood vessels. People who have prothrombin thrombophilia are at somewhat higher than average risk for a type of clot called a deep venous thrombosis, which typically occurs in the deep veins of the legs. Affected people also have an increased risk of developing a pulmonary embolism, which is a clot that travels through the bloodstream and lodges in the lungs. Most people with prothrombin thrombophilia never develop abnormal blood clots. The disorder is the propensity to venous thrombosis due to an abnormality in the coagulation system. It may be inherited or acquired, although in some cases the underlying cause has not been identified. Many factors contribute to the hypercoagulable state. Inherited thrombophilia affects up to 10% of the population; acquired risk factors, such as obesity and hormonal therapy, are frequent in the community. Most patients with heritable thrombophilia remain asymptomatic. Venous thromboembolism is the most common manifestation of the hypercoagulable state. It can be prevented in some patients with identification of those at risk and appropriate thromboprophylaxis during periods of high risk, such as admission to the hospital and following major surgery.
