Myelofibrosis

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Myelofibrosis is a serious bone marrow disorder that disrupts your body's normal production of blood cells. The result is extensive scarring in your bone marrow, leading to severe anemia, weakness, fatigue, and often, an enlarged spleen and liver. Myelofibrosis is a type of chronic leukemia - a cancer that affects the blood-forming tissues in the body. Myelofibrosis can occur on its own (primary myelofibrosis) or it can occur as a result of another bone marrow disorder (secondary myelofibrosis). Many people with myelofibrosis get progressively worse, and some may eventually develop a more serious form of leukemia. Yet it's also possible to have myelofibrosis and live symptom-free for years. Treatment for myelofibrosis, which focuses on relieving symptoms, can involve a variety of options.

Symptoms:

Laboratory Test Procedures:

vomiting
fatigue
shortness of breath
anemia
mucosal bleeding
prolonged bleeding
easy bruising
fever
increased number and severity of infections
joint aches
bone pain
swollen lymph nodes
swollen spleen
enlarged liver
swollen kidneys
swollen testicles
seizures
headache
confusion
weight loss
sweating

Tear Drop Cells
WBC
RBC
Platelet Count
Basophil %
Basophil Absolute
Ovalocytes
Protime/INR
PTT
D-dimer (fibrin degradation products)
DDxHub Differential Diagnosis online system provides with more lab test procedures...

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All information on this page is intended for your general knowledge only and does not provide medical advice, diagnosis or treatment. See Additional Information